Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1)

Seizo Koshiba, Takanori Kigawa, Junji Iwahara, Akira Kikuchi, Shigeyuki Yokoyama

研究成果: Article査読

24 被引用数 (Scopus)

抄録

The solution structure of the Eps15 homology (EH) domain of a human POB1 (partner of RalBP1) has been determined by uniform 13C/15N labeling and heteronuclear multidimensional nuclear magnetic resonance spectroscopy. The POB1 EH domain consists of two EF-hand structures, and the second one binds a calcium ion. In the calcium-bound state, the orientation of the fourth α-helix relative to the other helices of the POB1 EH domain is slightly different from that of calbindin, and much more different from those of calmodulin and troponin C, on the basis of their atomic coordinates. Copyright (C) 1999 Federation of European Biochemical Societies.

本文言語English
ページ(範囲)138-142
ページ数5
ジャーナルFEBS Letters
442
2-3
DOI
出版ステータスPublished - 1999 1月 15
外部発表はい

ASJC Scopus subject areas

  • 生物理学
  • 構造生物学
  • 生化学
  • 分子生物学
  • 遺伝学
  • 細胞生物学

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