siRNA-mediated inhibition of phosphatidylinositol glycan class B (PIGB) confers resistance to methylmercury in HEK293 cells

Gi Wook Hwang, Tatsuya Hayashi, Kayoko Kita, Tsutomu Takahashi, Shusuke Kuge, Akira Naganuma

研究成果: Article査読

5 被引用数 (Scopus)

抄録

We performed functional gene screening, using a siRNA library targeting 8,500 human genes, to identify proteins that are involved in the susceptibility of cells to methylmercury. Screening revealed that downregulation of the gene for phosphatidylinositol glycan class B (PIGB) by siRNA confers resistance to methylmercury in HEK293 cells.

本文言語English
ページ(範囲)581-583
ページ数3
ジャーナルJournal of Toxicological Sciences
32
5
DOI
出版ステータスPublished - 2007 12

ASJC Scopus subject areas

  • Toxicology

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