Simultaneous observation of cavitation bubbles generated in biological tissue by high-speed optical and acoustic imaging methods

Kai Suzuki, Ryosuke Iwasaki, Ryo Takagi, Shin Yoshizawa, Shin Ichiro Umemura

研究成果: Article査読

7 被引用数 (Scopus)

抄録

Acoustic cavitation bubbles are useful for enhancing the heating effect in high-intensity focused ultrasound (HIFU) treatment. Many studies were conducted to investigate the behavior of such bubbles in tissue-mimicking materials, such as a transparent gel phantom; however, the detailed behavior in tissue was still unclear owing to the difficulty in optical observation. In this study, a new biological phantom was developed to observe cavitation bubbles generated in an optically shallow area of tissue. Two imaging methods, high-speed photography using light scattering and highspeed ultrasonic imaging, were used for detecting the behavior of the bubbles simultaneously. The results agreed well with each other for the area of bubble formation and the temporal change in the region of bubbles, suggesting that both methods are useful for visualizing the bubbles.

本文言語English
論文番号07JF27
ジャーナルJapanese journal of applied physics
56
7
DOI
出版ステータスPublished - 2017 7

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

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