Simultaneous imaging of protonated and deprotonated carbonylcyanide p-trifluoromethoxyphenylhydrazone in live cells by Raman microscopy

Hiroyuki Yamakoshi; Almar F. Palonpon; Kosuke Dodo; Jun Ando; Satoshi S. Kawat; Katsumasa Fujita; Mikiko Sodeoka

doi:10.1039/c3cc48587k

Simultaneous imaging of protonated and deprotonated carbonylcyanide p-trifluoromethoxyphenylhydrazone in live cells by Raman microscopy

Hiroyuki Yamakoshi, Almar F. Palonpon, Kosuke Dodo, Jun Ando, Satoshi S. Kawat, Katsumasa Fujita, Mikiko Sodeoka

研究成果: Article › 査読

35 被引用数 (Scopus)

抄録

We report the simultaneous imaging of protonated and deprotonated forms of carbonylcyanide p-trifluoromethoxy-phenylhydrazone (FCCP) molecules in live cells by Raman microscopy. Nitriles, structure-sensitive Raman tags, are used to detect the two distinct molecular structures, demonstrating the potential of Raman microscopy for structure-based imaging of bioactive small molecules.

本文言語	English
ページ（範囲）	1341-1343
ページ数	3
ジャーナル	Chemical Communications
巻	50
号	11
DOI	https://doi.org/10.1039/c3cc48587k
出版ステータス	Published - 2014 1月 9
外部発表	はい

ASJC Scopus subject areas

触媒
電子材料、光学材料、および磁性材料
セラミックおよび複合材料
化学 (全般)
表面、皮膜および薄膜
金属および合金
材料化学

文献へのアクセス

10.1039/c3cc48587k

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引用スタイル

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abstract = "We report the simultaneous imaging of protonated and deprotonated forms of carbonylcyanide p-trifluoromethoxy-phenylhydrazone (FCCP) molecules in live cells by Raman microscopy. Nitriles, structure-sensitive Raman tags, are used to detect the two distinct molecular structures, demonstrating the potential of Raman microscopy for structure-based imaging of bioactive small molecules.",

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AU - Yamakoshi, Hiroyuki

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AU - Dodo, Kosuke

AU - Ando, Jun

AU - Kawat, Satoshi S.

AU - Fujita, Katsumasa

AU - Sodeoka, Mikiko

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