Simple organocatalyst component system for asymmetric hetero Diels-Alder reaction of isatins with enones

Perumalsamy Parasuraman, Zubeda Begum, Madhu Chennapuram, Chigusa Seki, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Suguru Tokiwa, Mitsuhiro Takeshita, Hiroto Nakano

研究成果: Article査読

1 被引用数 (Scopus)

抄録

A simple two catalyst component system consisting of primary β-amino alcohols as a catalyst and amino acids as a co-catalyst put together works as an efficient organocatalyst system in the hetero Diels-Alder reaction of isatins with enones to afford the chiral spirooxindole-tetrahydropyranones in good chemical yields and stereoselectivities (up to 86%, up to 85 : 15 dr., up to 95% ee).

本文言語English
ページ(範囲)17486-17491
ページ数6
ジャーナルRSC Advances
10
30
DOI
出版ステータスPublished - 2020 5 5

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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