TY - JOUR
T1 - Simple green synthesis of amino acid functionalised CdTe/CdSe/ZnSe core-multi shell with improved cell viability for cellular imaging
AU - Ncapayi, Vuyelwa
AU - Parani, Sundararajan
AU - Songca, Sandile P.
AU - Kodama, Tetsuya
AU - Oluwafemi, Oluwatobi S.
N1 - Funding Information:
The authors would like to thank the National Research Foundation (NRF), South Africa under the Nanotechnology Flagship Programme (Grant No: 97983) for financial support.
Publisher Copyright:
© 2016 Elsevier B.V.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2017/2/15
Y1 - 2017/2/15
N2 - We herein report a simple, economical and green synthesis of highly fluorescent, water soluble and stable arginine functionalised CdTe/CdSe/ZnSe multi core-shell nanoparticles (NPs) with enhanced cell viability for cellular imaging. The synthesis of the CdTe/CdSe/ZnSe NPs was carried out under ambient conditions in the absence of an inert environment. The as-prepared NPs were characterised using UV–vis absorption and photoluminescence (PL) spectroscopy, energy dispersive spectroscopy (EDS) and high resolution transmission electron microscopy (HRTEM). The optical analyses showed an enhancement in the fluorescent intensity after the functionalisation with improved optical properties. The functionalised NPs (F-NPs) displayed higher cell viability compared to the bare NPs when investigated on KM-Luc/GFP cell line at different concentrations. The fluorescent image indicated that the as-synthesised functionalised NPs were taken up by the cells.
AB - We herein report a simple, economical and green synthesis of highly fluorescent, water soluble and stable arginine functionalised CdTe/CdSe/ZnSe multi core-shell nanoparticles (NPs) with enhanced cell viability for cellular imaging. The synthesis of the CdTe/CdSe/ZnSe NPs was carried out under ambient conditions in the absence of an inert environment. The as-prepared NPs were characterised using UV–vis absorption and photoluminescence (PL) spectroscopy, energy dispersive spectroscopy (EDS) and high resolution transmission electron microscopy (HRTEM). The optical analyses showed an enhancement in the fluorescent intensity after the functionalisation with improved optical properties. The functionalised NPs (F-NPs) displayed higher cell viability compared to the bare NPs when investigated on KM-Luc/GFP cell line at different concentrations. The fluorescent image indicated that the as-synthesised functionalised NPs were taken up by the cells.
KW - CdTe/CdSe/ZnSe
KW - Functionalisation
KW - KM-Luc/GFP cell, arginine
KW - Nanoparticles
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U2 - 10.1016/j.matlet.2016.12.006
DO - 10.1016/j.matlet.2016.12.006
M3 - Article
AN - SCOPUS:85004019882
VL - 189
SP - 168
EP - 171
JO - Materials Letters
JF - Materials Letters
SN - 0167-577X
ER -