We demonstrate shape deformations of multicomponent vesicles from an experimental point of view. Phase separation of multicomponent vesicles causes a line tension at the domain boundary, a local bending modulus, and a local spontaneous curvature on the vesicles, which leads to unique shape deformation pathways. Especially, binary vesicles composed of lipids having different spontaneous curvatures show functional shape deformations, such as adhesion, pore formation, and lipid sorting. These observations provide the physical basis for shape deformations in cellular membranes.
|ジャーナル||Advances in Planar Lipid Bilayers and Liposomes|
|出版ステータス||Published - 2010|
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