TY - JOUR
T1 - Shape deformations of multicomponent vesicles
AU - Imai, Masayuki
AU - Sakuma, Yuka
PY - 2010
Y1 - 2010
N2 - We demonstrate shape deformations of multicomponent vesicles from an experimental point of view. Phase separation of multicomponent vesicles causes a line tension at the domain boundary, a local bending modulus, and a local spontaneous curvature on the vesicles, which leads to unique shape deformation pathways. Especially, binary vesicles composed of lipids having different spontaneous curvatures show functional shape deformations, such as adhesion, pore formation, and lipid sorting. These observations provide the physical basis for shape deformations in cellular membranes.
AB - We demonstrate shape deformations of multicomponent vesicles from an experimental point of view. Phase separation of multicomponent vesicles causes a line tension at the domain boundary, a local bending modulus, and a local spontaneous curvature on the vesicles, which leads to unique shape deformation pathways. Especially, binary vesicles composed of lipids having different spontaneous curvatures show functional shape deformations, such as adhesion, pore formation, and lipid sorting. These observations provide the physical basis for shape deformations in cellular membranes.
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U2 - 10.1016/B978-0-12-381266-7.00003-1
DO - 10.1016/B978-0-12-381266-7.00003-1
M3 - Article
AN - SCOPUS:77958175172
VL - 12
SP - 41
EP - 78
JO - Advances in Biomembranes and Lipid Self-Assembly
JF - Advances in Biomembranes and Lipid Self-Assembly
SN - 2451-9634
IS - C
ER -