Serum albumin-treated sn-38 prodrug nanoparticles toward cancer treatment

研究成果: Article査読

抄録

Carrier-free drug nanoparticles are emerging as a next generation of drug delivery systems. Herein, we worked on improving their dispersion stability in the physiological environment by employing serum albumin protein. With anticancer SN-38 prodrug nanoparticles (NPs) and bovine serum albumin (BSA) as model studies, it was found that BSA prevented SN-38 NPs from aggregating in phosphate buffered saline, and the resulted nanoparticle dispersion becomes stable while maintains their anticancer efficiency.

本文言語English
ページ(範囲)1555-1558
ページ数4
ジャーナルChemistry Letters
50
8
DOI
出版ステータスPublished - 2021 8

ASJC Scopus subject areas

  • 化学 (全般)

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