Separation of oligonucleotides with single-base mutation by capillary electrophoresis using specific interaction of metal ion with nucleotide

Toru Takahashi, Takao Sakurai, Koichiro Hirata, Hitoshi Hoshino

研究成果: Article査読

4 被引用数 (Scopus)

抄録

A unique tactic for the separation of single-base sequential isomers of oligomeric single-stranded DNA by a CE separation system employing the specific interaction of metal ion with nucleotide was demonstrated, enabling the separation of the mixture of a 12-mer oligonucleotide and its single-base mutants, as well as their positional isomers.

本文言語English
ページ(範囲)1299-1301
ページ数3
ジャーナルAnalyst
134
7
DOI
出版ステータスPublished - 2009

ASJC Scopus subject areas

  • 分析化学
  • 生化学
  • 環境化学
  • 分光学
  • 電気化学

フィンガープリント

「Separation of oligonucleotides with single-base mutation by capillary electrophoresis using specific interaction of metal ion with nucleotide」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル