Self-spreading supported lipid bilayer passing through single nanogap structure: Effect of position of dyes in lipid molecules

Yoshiaki Kashimura, Kazuaki Furukawa, Keiichi Torimitsu

研究成果: Article査読

4 被引用数 (Scopus)

抄録

We report the self-spreading behavior of single lipid bilayers containing 7-nitrobenz-2-oxa-1, 3-diazol-4-yl (NBD) fluorophores on a patterned surface equipped with a single nanogap. We found that the behavior of the fluorophores around the nanogap depended on the position of the dyes in the lipid molecules. For acyl chain-labeled lipids, the fluorescence intensities decreased discontinuously before and after they passed through the nanogap, whereas little decrease was observed for a headgroup-labeled lipid. A possible mechanism can be explained in terms of the reorientation of dyes in a lipid bilayer. Acyl chain-labeled NBD fluorophores are known to loop back to a lipid-water interface in a lipid bilayer. Since this effect makes an effective size of the lipid molecule larger, dye molecules easily suffer from steric hindrance when they pass through a nanogap leading to the fluorescence intensity reduction.

本文言語English
論文番号04DL15
ジャーナルJapanese journal of applied physics
49
4 PART 2
DOI
出版ステータスPublished - 2010 4 1
外部発表はい

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

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