@article{4b24c9cdddfa406b98e1426ddef38e3a,
title = "Self-formation of bilayer lipid membranes on agarose-coated silicon surfaces studied by simultaneous electrophysiological and surface infrared spectroscopic measurements",
abstract = "Self-formation process of bilayer lipid membranes (BLMs) cushioned on agarose-coated Si surfaces was in situ monitored by simultaneous electrophysiological and infrared absorption spectroscopic (IRAS) measurements using IRAS with the multiple internal reflection geometry. IRAS signals corresponding to self-thinning of lipid solution to form BLMs were demonstrated. It was found that the appearance of IRAS bands due to C=O modes of phosphstidylcholine is related to formation of BLMs with a gigaohm seal. The functionality of the present BLM system was also demonstrated by incorporating gramicidin into the BLMs and recording its channel activities.",
author = "Ayumi Hirano-Iwata and Azusa Oshima and Kota Onodera and Kouji Aoto and Tasuku Taira and Yamaguchi, {Ryo Taro} and Yasuo Kimura and Michio Niwano",
note = "Funding Information: This work was supported by Grants-in-Aid for Basic Scientific Research (Grant Nos. 20246008 and 19750056) from the Ministry of Education, Science, Sports, and Culture of Japan. Financial supports from Takeda Science Foundation and The Asahi Glass Foundation are also acknowledged. We are grateful to Professor Yoshio Umezawa, Musashino University, for his kind support of the electrophysiological measurements.",
year = "2009",
doi = "10.1063/1.3140206",
language = "English",
volume = "94",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics Publising LLC",
number = "24",
}