Selenoprotein P; P for plasma, prognosis, prophylaxis, and more

研究成果: Review article査読

8 被引用数 (Scopus)

抄録

Selenoprotein P (SeP) is one of the 25 human selenocysteine (Sec)-containing proteins, and is generally thought to function as a plasma carrier of the trace element selenium in the body. Recent studies, however, indicate unsuspected pivotal roles of SeP in human diseases, particularly in type 2 diabetes mellitus (T2DM) and pulmonary arterial hypertension (PAH). In this review, we will summarize the characteristics of SeP and recent advances in the field, especially focusing on the emerging roles of SeP in pathophysiological conditions. We will also discuss potential medical/pharmaceutical applications targeting SeP.

本文言語English
ページ(範囲)366-374
ページ数9
ジャーナルBiological and Pharmaceutical Bulletin
43
3
DOI
出版ステータスPublished - 2020 3 1

ASJC Scopus subject areas

  • 薬理学
  • 薬科学

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