Renal pathology of ANCA-related vasculitis: Proposal for standardization of pathological diagnosis in Japan

Kensuke Joh, Eri Muso, Hidekazu Shigematsu, Masato Nose, Michio Nagata, Yoshihiro Arimura, Wako Yumura, Takashi Wada, Kousaku Nitta, Hirofumi Makino, Yoshio Taguma, Hidetoshi Kaneoka, Yuhsuke Suzuki, Masaki Kobayashi, Akio Koyama, Joichi Usui, Hiroshi Hashimoto, Shoichi Ozaki, Yasuhiko Tomino, Kunihiro Yamagata

研究成果: Article査読

18 被引用数 (Scopus)

抄録

Background: In Japan, systematic evaluation of the histologic parameters of anti-neutrophil cytoplasmic autoantibodies (ANCA)-related vasculitis has been performed according to the Japanese classification by Shigematsu et al. However, this classification is quite different from that of the European Vasculitis Study Group (EUVAS) classification. Therefore, a histological common basis is needed to compare Japanese histological data with the international database. Method: Histological parameters concerning glomerular, tubulointerstitial, and vascular lesions of ANCA-related vasculitis, which are indispensable for clinical management, were elucidated and defined by reviewing, utilizing the merits of, and amending the two scoring systems. Results and conclusion: A new comprehensive and standardized scoring system, by which histological quantitative assessment can provide evidence for therapy planning, has been developed for renal biopsy of Japanese ANCA-related vasculitis.

本文言語English
ページ(範囲)277-291
ページ数15
ジャーナルClinical and experimental nephrology
12
4
DOI
出版ステータスPublished - 2008 8

ASJC Scopus subject areas

  • Physiology
  • Nephrology
  • Physiology (medical)

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