Reinitiation of meiosis in starfish oocytes requires an increase in nuclear ca2+

Luigia Santella, Keiichiro Kyozuka

研究成果: Article査読

60 被引用数 (Scopus)

抄録

Here we report that an increase in nuclear Ca2+ is hormonally regulated and is required for reinitiation of meiosis in starfish oocytes. We have shown in Asteria pectirtifera that a Ca2+ transient and a baseline increase of Ca2+ occur both in the cytoplasm and in the nucleus. These increases are in response to 1-methyladenine (1-MA), the hormone responsible for the induction of meiotic maturation. The Ca2+ transients are not necessary for the reinitiation of meiosis. However, blocking the baseline increase in nuclear Ca2+ blocks both the nuclear envelope breakdown (NEBD) and the continuation of meiosis.

本文言語English
ページ(範囲)674-680
ページ数7
ジャーナルBiochemical and biophysical research communications
203
1
DOI
出版ステータスPublished - 1994 8 30

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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