Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain

Yasuhiro Hakamata, Junichi Nakai, Hiroshi Takeshima, Keiji Imoto

研究成果: Article査読

338 被引用数 (Scopus)

抄録

The complete amino acid sequence of a novel ryanodine receptor/calcium release channel from rabbit brain has been deduced by cloning and sequence analysis of the EDNA. This protein is composed of 4872 amino acids and shares characteristic structural features with the skeletal muscle and cardiac ryanodine receptors. RNA blot hybridization analysis shows that the brain ryanodine receptor is abundantly expressed in corpus striatum, thalamus and hippocampus, whereas the cardiac ryanodine receptor is more uniformly expressed in the brain. The brain ryanodine receptor gene is transcribed also in smooth muscle.

本文言語English
ページ(範囲)229-235
ページ数7
ジャーナルFEBS Letters
312
2-3
DOI
出版ステータスPublished - 1992 11 9
外部発表はい

ASJC Scopus subject areas

  • 生物理学
  • 構造生物学
  • 生化学
  • 分子生物学
  • 遺伝学
  • 細胞生物学

フィンガープリント

「Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル