Prevalence of senile dementia in a rural community in Japan: The Tajiri project

Hiroshi Ishii, Kenichi Meguro, Junichi Ishizaki, Masumi Shimada, Satoshi Yamaguchi, Iwao Sano, Hideo Ambo, Hiroya Ohtake, Yoichi Shimada, Kyoko Someya, Mari Sato, Yuka Shibuya, Masami Kato, Yasuyoshi Sekita, Atsushi Yamadori

研究成果: Article査読

20 被引用数 (Scopus)

抄録

Knowledge of the prevalence of dementia in different age groups is needed for the planning of a health policy. This study shows the prevalence of dementia and magnetic resonance imaging (MRI) findings in elderly people aged 65 years and over, living in the town of Tajiri in the northern part of Japan. They were shown by two cognitive screening tests, the Mini-Mental State examination (MMS) and the Dementia Screening Test (DST) and medical diagnosis. Two subject groups were assessed, those who completed both tests (Subjects I, n = 2066) and those from among the 200 'MRI-administered subjects' who were interviewed and diagnosed (Subjects II, n = 170). For Subjects I, there were 6.3 and 10.2% 'dementia range' according to the severe and mild criteria, respectively. As for Subjects II, 9.4% were clinically diagnosed as having dementia. They met the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria of probable Alzheimer's disease (AD) or possible AD with cerebrovascular disease. The estimated prevalence rate of dementia was 8.0%. Visual ratings of brain atrophy using MRI disclosed two distribution patterns. The 'continuous' pattern of the frontal and temporal lobes atrophy suggest that both are affected by the aging process, while a 'discontinuous' pattern of the hippocampal atrophy could indicate a pathologic background such as early changes of AD.

本文言語English
ページ(範囲)249-265
ページ数17
ジャーナルArchives of Gerontology and Geriatrics
29
3
DOI
出版ステータスPublished - 2000 2

ASJC Scopus subject areas

  • 健康(社会科学)
  • 加齢科学
  • 老年学
  • 老年医学

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