Hydroxyapatite (HA) porous ceramics are useful for bone regeneration because HA shows a bone-bonding capability. The preparation of HA porous ceramics with controlled pore structures was attempted using a hydrothermal treatment of porous ceramics consisting of alpha tricalcium phosphate (α-TCP). The α-TCP porous ceramics were hydrothermally treated with various aqueous solutions containing NaCl, CaCl2, Na 3PO4, Na2HPO4, NaH 2PO4, or H3PO4 at 150°C for a period of 10 h. The α-TCP phase of the porous ceramics was transformed into HA by the hydrothermal treatment in ultrapure water, NaCl, CaCl 2, Na3PO4 or Na2HPO4 solutions, to form porous ceramics consisting of rod-shaped HA particles. The size of the rod-shaped HA particles prepared in Na3PO4 or Na2HPO4 solutions was smaller than that prepared in ultrapure water, NaCl, or CaCl2 solutions. The α-TCP phase of the porous ceramics was transformed into a biphase consisting of HA and monetite (DCPA) after treatment in NaH2PO4 solution, and into DCPA in the H3PO4 solution, resulting in porous ceramics consisting of plate-shaped particles. These results indicate that we could control the size and shape of the HA particles using the hydrothermal conditions, and this also provides a way of controlling the porous structure of the HA porous ceramics.
ASJC Scopus subject areas
- 化学 (全般)