Preparation of hybrid-type vascular prosthesis using phospholipid polymer surfaces with cell substitution function

Kayahiko Makita, Ryuzea Miura, Sang Mo Ye, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

研究成果: Paper査読

抄録

The purpose of the research is preparation of a new-type hybrid artificial blood vessel with small inner diameter less than 4mm. We paid attention 10 the mechanical property and blood compatibility of the material for preparing the artificial blood vessel. As a core material, segmented polyurethane was used. The inner surface of the artificial blood vessel should have an excellent antithrombogenicity at early stage after implantation and it goes adhesiveness of human umbilical endothelial cells. Thus, the surface should be covered with a blood compatible phospholipid polymer, that is, 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer. The appearance where smooth muscle cells invade on the substrate coated with MPC polymer was observed.

本文言語English
ページ数1
出版ステータスPublished - 2006 10 19
外部発表はい
イベント55th SPSJ Annual Meeting - Nagoya, Japan
継続期間: 2006 5 242006 5 26

Other

Other55th SPSJ Annual Meeting
国/地域Japan
CityNagoya
Period06/5/2406/5/26

ASJC Scopus subject areas

  • 工学(全般)

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