Power laws for spontaneous neuronal activity in hippocampal CA3 slice culture

Toshikazu Samura, Yasuomi D. Sato, Yuji Ikegaya, Hatsuo Hayashi

研究成果: Conference contribution

抄録

We study on computer simulations to infer a network structure of the hippocampal CA3 culture slice, which is not yet found even in physiological experiments. In order to find the network structure, we have to understand dynamical mechanisms of how to establish two power law distributions of spontaneous activities observed in the CA3 cultured slice. The first power law is the probabilistic distribution of firing frequency in a neuron. The second is of synchrony size that means a rate of co-active neurons within a time bin. In this work, we show that the power law observations significantly rely on the two network mechanisms: (1) high-frequency firing of interneurons by feedback from pyramidal cells, (2) log-normal distribution of synaptic weights.

本文言語English
ホスト出版物のタイトルNeural Information Processing - 18th International Conference, ICONIP 2011, Proceedings
ページ370-379
ページ数10
PART 1
DOI
出版ステータスPublished - 2011
イベント18th International Conference on Neural Information Processing, ICONIP 2011 - Shanghai, China
継続期間: 2011 11 132011 11 17

出版物シリーズ

名前Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
番号PART 1
7062 LNCS
ISSN(印刷版)0302-9743
ISSN(電子版)1611-3349

Other

Other18th International Conference on Neural Information Processing, ICONIP 2011
CountryChina
CityShanghai
Period11/11/1311/11/17

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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