Portopulmonary hypertension: Hemodynamics, pulmonary angiography, and configuration of the heart

Masahito Sakuma, Shinko Souma, Osamu Kitamukai, Jun Demachi, Tohru Takahashi, Jun Suzuki, Jun Nawata, Kouichiro Sugimura, Minako Oikawa, Kenya Saji, Tomohiro Tada, Shigefumi Fukui, Yutaka Kagaya, Jun Watanabe, Kunio Shirato

研究成果: Article査読

8 被引用数 (Scopus)

抄録

Background: The goal of the present study was to examine the cardiac configuration and pulmonary vascular changes in patients with portopulmonary hypertension (PPHTN) and compare them with those of idiopathic pulmonary arterial hypertension (IPAH). Methods and Results: The subjects were 10 patients with PPHTN and 18 with IPAH. In PPHTN, the increases in the right ventricular end-diastolic volume index (89±19 vs 128±50ml/m2; p=0.04), right end-systolic volume index (50±19 vs 95±47ml/m 2; p=0.02) and right ventricular mass index (47±18g/m 2 vs 79±31; p=0.04) were low compared with IPAH. The decrease in the right ventricular ejection fraction was also low in PPHTN (45±10 vs 28±13%; p=0.01). The degree of sparse arborization and abrupt narrowing on wedged pulmonary angiography was moderate in PPHTN compared with IPAH. In PPHTN, the proximal pulmonary arteries were dilated near the segmental arteries, which were narrow in IPAH. Conclusion: Changes in the configuration of the heart were moderate in PPHTN compared with those in IPAH. The degree of sparse arborization and abrupt narrowing were also moderate in PPHTN.

本文言語English
ページ(範囲)1386-1393
ページ数8
ジャーナルCirculation Journal
69
11
DOI
出版ステータスPublished - 2005

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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