Pokkuri, a Drosophila gene encoding an E-26-specific (Ets) domain protein, prevents overproduction of the R7 photoreceptor

Hajime Tei, Itsuko Nihonmatsu, Takakazu Yokokura, Ryu Ueda, Yumiko Sano, Takashi Okuda, Kanako Sato, Kanako Hirata, Shinobu C. Fujita, Daisuke Yamamoto

研究成果: Article査読

52 被引用数 (Scopus)

抄録

Studies on sevenless and bride of sevenless genes have revealed that the R8 cell plays a key role in the fate of the R7 photoreceptor cell, presenting on its surface an inductive cue to which R7 responds, sev-independent induction of R7 cells has been reported in the seven-up mutation, which appears to transform R1 and R6 cells to R7 cells. We have induced recessive mutations in a gene pokkuri (pok; pokkuri is a Japanese word that means "dropping dead") that lead to overproduction of R7 cells with rather minor effects on outer photoreceptors and R8 cells. Pok protein may function as a transcription factor, as the predicted amino acid sequence contains a region similar to the consensus established for the E-26-specific (Ets) domain.

本文言語English
ページ(範囲)6856-6860
ページ数5
ジャーナルProceedings of the National Academy of Sciences of the United States of America
89
15
DOI
出版ステータスPublished - 1992
外部発表はい

ASJC Scopus subject areas

  • 一般

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