PMab-48 Recognizes Dog Podoplanin of Lymphatic Endothelial Cells

Shinji Yamada, Shunsuke Itai, Mika K. Kaneko, Yukinari Kato

研究成果: Article査読

10 被引用数 (Scopus)

抄録

Podoplanin, a type I transmembrane glycoprotein, is a specific marker of lymphatic endothelial cells (LECs). Recently, we developed PMab-38, an anti-dog podoplanin monoclonal antibody that did not stain canine LECs. In this study, we newly developed PMab-48 against dog podoplanin. Immunohistochemical analysis revealed that PMab-48 reacts not only with canine squamous cell carcinoma cells but also with LECs of the normal colon. Therefore, PMab-48 may be useful in investigating the function of dog podoplanin in LECs.

本文言語English
ページ(範囲)63-66
ページ数4
ジャーナルMonoclonal antibodies in immunodiagnosis and immunotherapy
37
1
DOI
出版ステータスPublished - 2018 2

ASJC Scopus subject areas

  • 免疫アレルギー学
  • 免疫学

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