Physiology: Distribution of tenascin in normal cycling human ovary

M. Tamura, H. Sasano, T. Suzuki, T. Fukaya, T. Watanabe, M. Kusakabe, T. Sakakura, A. Yajima

研究成果: Article査読

9 被引用数 (Scopus)

抄録

Tenascin is an extracellular matrix glycoprotein, which has been reported to be involved in parenchymal-mesenchymal interactions during morphogenesis, wound healing, and carcinogenesis. Tenascin immunolocalization was performed in 51 specimens of morphologically normal human ovaries by using a specific monoclonal antibody against purified human fibroblast tenascin. In preovulatory follicles, no significant immunoreactivity was detected. In functioning corpora lutea, immunoreactivity was present as a fine border around the periphery. In association with the involution of the corpora lutea, marked diffuse tenascin immunostaining in the intercellular space was observed. These data raise the question of whether tenascin may be involved in luteolysis and may play an important role in the ovarian cycle by regulating the involution of corpora lutea.

本文言語English
ページ(範囲)2015-2018
ページ数4
ジャーナルHuman Reproduction
8
12
DOI
出版ステータスPublished - 1993 12

ASJC Scopus subject areas

  • 生殖医学
  • 産婦人科学

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