Photophysical investigations of squaraine and cyanine dyes and their interaction with bovine serum albumin

M. Saikiran, D. Sato, S. S. Pandey, T. Kato

研究成果: Conference article査読

3 被引用数 (Scopus)

抄録

A model far-red sensitive symmetrical squaraine dye (SQ-3) and unsymmetrical near infra-red sensitive cyanine dye (UCD-1) bearing direct-COOH functionalized indole ring were synthesized, characterized and subjected to photophysical investigations including their interaction with bovine serum albumin (BSA) as a model protein in phosphate buffer solution (PBS). Both of the dyes exhibit strong interaction with BSA in phosphate buffer with high apparent binding constant. A judicious tuning of hydrophobic main backbone with reactive functionality for associative interaction with active site of BSA has been found to be necessary for BSA detection in PBS.

本文言語English
論文番号012012
ジャーナルJournal of Physics: Conference Series
704
1
DOI
出版ステータスPublished - 2016 4月 19
イベントIndia-Japan Expert Group Meeting on Biomolecular Electronics and Organic Nanotechnology for Environment Preservation, IJEGMBE 2015 - Fukuoka, Japan
継続期間: 2015 12月 232015 12月 26

ASJC Scopus subject areas

  • 物理学および天文学(全般)

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