Methane hydrate (MH) is expected as a new energy source. To predict gas productivity from a MH sediment, it is necessary to make numerical model for various phenomena in order to develop a numerical simulator and carry out some parametric study for various reservor conditons and production methods. In this study, we have carried out measurements of permeability by using artificial MH sediments. To reproduce the flow condition of gas and water in a real MH field, we attempted to measure the permeability of artificial MH sediment under the horizontal radial flow condition by using disc shape samples. From experimental results, the relationship between MH saturation and permeability was clarified, and we discussed permeability change in the process of MH dissociation by depressurization.