Perifolliculitis capitis abscedens et suffodiens treatment with tumor necrosis factor inhibitors: A case report and review of published cases

Toshiya Takahashi, Kenshi Yamasaki, Hitoshi Terui, Ryoko Omori, Kenichiro Tsuchiyama, Taku Fujimura, Setsuya Aiba

研究成果: Article査読

12 被引用数 (Scopus)

抄録

Perifolliculitis capitis abscedens et suffodiens (PCAS) or dissecting cellulitis is a rare condition presenting deep follicular occlusions, follicular ruptures and follicular infections in the scalp area with unknown etiology, which consequently cause primary neutrophilic cicatricial alopecia by the repeated follicular inflammation. PCAS is categorized as one of the “follicular occlusion tetrad” along with hidradenitis suppurativa, acne conglobata and pilonidal cyst. In the pathogenesis of the follicular occlusion tetrad, the involvement of neutrophils and its activator tumor necrosis factor (TNF) have been discussed. Here, we report a case of PCAS that was successfully treated with adalimumab, a human anti-TNF monoclonal antibody. This is the first Asian case of PCAS that was improved by a TNF inhibitor.

本文言語English
ページ(範囲)802-807
ページ数6
ジャーナルJournal of Dermatology
46
9
DOI
出版ステータスPublished - 2019 9 1

ASJC Scopus subject areas

  • 皮膚病学

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