Pancreatic acinar cell carcinoma with multiple liver metastases effectively treated by S-1 chemotherapy

Naoki Yoshida, Atsushi Kanno, Atsushi Masamune, Tatsuhide Nabeshima, Seiji Hongo, Shin Miura, Tetsuya Takikawa, Shin Hamada, Kazuhiro Kikuta, Kiyoshi Kume, Masamichi Ueno, Tooru Shimosegawa

研究成果: Article査読

1 被引用数 (Scopus)

抄録

A 79-year-old woman was referred for pancreatic tail cancer with multiple liver metastases. The pancreatic tail tumor was diagnosed as acinar cell carcinoma (ACC) histologically by endoscopic ultrasound-guided fine-needle aspiration. Because of multiple liver metastases, S-1 chemotherapy was administered, resulting in a partial response to chemotherapy one year later. After approximately three years, liver atrophy and esophageal varices developed. We suspected S-1 as the cause of the liver cirrhosis. S-1 cessation minimized ascites and improved the esophageal varices. Although S-1 can potentially treat ACC, we should be watchful for liver cirrhosis caused by its long-term administration.

本文言語English
ページ(範囲)3529-3535
ページ数7
ジャーナルInternal Medicine
57
24
DOI
出版ステータスPublished - 2018

ASJC Scopus subject areas

  • 内科学

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