Palladium(0)-catalyzed alkylative cyclization of alkynals and alkynones: Remarkable trans-addition of organoboronic reagents

Hirokazu Tsukamoto, Tatsuhiko Ueno, Yoshinori Kondo

研究成果: Article査読

62 被引用数 (Scopus)

抄録

Palladium/monophosphine complexes catalyze trans-selective arylative, alkenylative, and alkylative cyclization reactions of alkynals and alkynones with organoboronic reagents. These reactions afford six-membered allylic alcohols with endo-tri- or tetrasubstituted olefin groups and/or five-membered counterparts with exo olefin groups. The ratios of these products are dramatically affected by alkyne substituents as well as the phosphine ligand. The remarkable trans-selectivity of the process results from the novel reaction mechanism involving oxidative addition without oxametallacycle formation.

本文言語English
ページ(範囲)1406-1407
ページ数2
ジャーナルJournal of the American Chemical Society
128
5
DOI
出版ステータスPublished - 2006 2月 8

ASJC Scopus subject areas

  • 触媒
  • 化学 (全般)
  • 生化学
  • コロイド化学および表面化学

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