Palladium-catalyzed hydrocarbonation and hydroamination of 3,3-dihexylcyclopropene with pronucleophiles

Itaru Nakamura, Gan B. Bajracharya, Yoshinori Yamamoto

研究成果: Article査読

65 被引用数 (Scopus)

抄録

The reaction of 3,3-dihexylcyclopropene 1 with carbon and amine pronucleophiles 2 in the presence of palladium catalysts proceeded smoothly to give the corresponding hydrocarbonation products 3, allylated nucleophiles, in good to high yields. For example, in the presence of catalytic amounts of Pd(PPh3)4 and dppf, the reaction of 3,3-dihexylcyclopropene with ethyl 2-cyanopropionate and ethyl 2-cyanophenylacetate gave ethyl 2-cyano-2-methyl-4-undecenoate and ethyl 2-cyano-2-phenyl-4-undecenoate in 82 and 86% yield, respectively.

本文言語English
ページ(範囲)2297-2299
ページ数3
ジャーナルJournal of Organic Chemistry
68
6
DOI
出版ステータスPublished - 2003 3月 21

ASJC Scopus subject areas

  • 有機化学

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