Palladium-Catalyzed Condensation of Aryl Halides with Phenylsulfonylacetonitrile and Diethyl Cyanomethylphosphonate

Takao Sakamoto, Eisaku Katoh, Yoshinori Kondo, Hiroshi Yamanaka

研究成果: Article査読

22 被引用数 (Scopus)

抄録

The palladium(0)-catalyzed condensation of aryl halides with the sodium salts of phenylsulfonylacetonitrile and diethyl cyanomethylphosphonate in dimethoxyethane gave the corresponding α-phenylsulfonylareneacetonitriles and diethyl arylcyanomethylphosphonates in good yields. The α-phenylsulfonylareneacetonitriles were easily desulfonylated with zinc to give the areneacetonitriles, and the arylcyanomethylphosphonates were converted to the alkylideneareneacetonitriles by means of the Horner-Emmons reaction.

本文言語English
ページ(範囲)1513-1517
ページ数5
ジャーナルChemical and Pharmaceutical Bulletin
38
6
DOI
出版ステータスPublished - 1990

ASJC Scopus subject areas

  • 化学 (全般)
  • 創薬

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