@article{319d16bc82094d24995142d9735badff,
title = "Organocatalytic activity of 4-hydroxy-prolinamide alcohol with different noncovalent coordination sites in asymmetric Michael and direct aldol reactions",
abstract = "4-Hydroxy-prolinamide alcohol with different noncoordination sites as a molecule showed excellent asymmetric catalytic activity in both the Michael reaction (up to 98% ee) and the direct aldol reaction (up to >99% ee), and the catalyzing reactions with high enantioselectivity are supported by a DFT theoretical study of their transition state.",
keywords = "4-Hydroxy-prolinamide alcohol, Aldol reaction, DFT calculations, Michael reaction, Organocatalyst",
author = "Yuko Okuyama and Hiroto Nakano and Yuki Watanabe and Mika Makabe and Mitsuhiro Takeshita and Koji Uwai and Chizuko Kabuto and Eunsang Kwon",
year = "2009",
month = jan,
day = "14",
doi = "10.1016/j.tetlet.2008.10.122",
language = "English",
volume = "50",
pages = "193--197",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "2",
}