Optimal selection method for establishing an inbred strain of laboratory animals with high performance for litter size at weaning

Masahiro Satoh, Kazuo Ishii

研究成果: Article査読

抄録

The optimal selection method was investigated for establishing an inbred strain of laboratory animals with high performance for litter size at weaning (LSW). A Monte Carlo computer simulation was used to assess the effects of our selection methods on the genetic change of LSW under the continuous use of full-sib mating for 20 generations. Smaller number of growing animals of each sex per litter and genetic evaluation for selection using a BLUP animal model increased LSW. Use of information on another trait genetically related to LSW, larger population size, and greater number of generations for random selection before starting full-sib mating were useful for establishing an inbred strain of laboratory animals with high performance for LSW. It was concluded that LSW can be increased by directional selection when establishing inbred strains.

本文言語English
ページ(範囲)152-157
ページ数6
ジャーナルAnimal Science Journal
79
2
DOI
出版ステータスPublished - 2008 4月 1
外部発表はい

ASJC Scopus subject areas

  • 農業および生物科学(全般)

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