One-Step conversion to a disubstituted cyclopentenone from 2-Deoxy-D-Glucose and application to synthesis of prostaglandin e1 methyl ester

Takaaki Kamishima, Toshiyuki Nonaka, Toshihiro Watanabe, Yoshitaka Koseki, Hitoshi Kasai

    研究成果: Article査読

    3 被引用数 (Scopus)

    抄録

    We have developed a facile one-step conversion of 2-deoxy-D-glucose to form a disubstituted cyclopentenone through catalyst-free hydrothermal reaction under mild conditions. The use of 2-deoxy-D-glucose in one-pot conversion is to provide the formation of a carbon five-membered ring instead of the common biomass-derived furans such as furfural, 5-HMF, etc. The cyclopentenone has a potential to be a building block for the preparation of chemical products. As one example, we successfully demonstrated the synthesis of prostaglandin E1 methyl ester.

    本文言語English
    ページ(範囲)1691-1696
    ページ数6
    ジャーナルBulletin of the Chemical Society of Japan
    91
    12
    DOI
    出版ステータスPublished - 2018 1 1

    ASJC Scopus subject areas

    • 化学 (全般)

    フィンガープリント

    「One-Step conversion to a disubstituted cyclopentenone from 2-Deoxy-D-Glucose and application to synthesis of prostaglandin e<sub>1</sub> methyl ester」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

    引用スタイル