Omalizumab, a monoclonal antibody to human IgE, is used to treat severe asthma and is reportedly effective in other allergic diseases. We report a case of eosinophilic otitis media and sinusitis improved by omalizumab treatment. A 66-year-old woman with severe asthma, eosinophilic otitis media, and sinusitis had omalizumab started to treat asthma. Besides rapidly improving asthma symptoms, it ameliorated eosinophilic otitis media and sinusitis, confirming its hoped for effectiveness.
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