Numerical modeling of microvascular hemodynamics in plasmodium falciparum malaria

Yohsuke Imai, K. Nakaaki, H. Kondo, Takuji Ishikawa, C. T. Lim, Takami Yamaguchi

研究成果: Conference contribution

抄録

High concentrations of nitric oxide (NO) have previously been measured in human maxillary sinuses, but the transport rates between the sinus and the nose during normal breathing have not been quantified. In this study, NO transport has been investigated using published NO concentrations and production rates, computational fluid dynamics (CFD) and first-order modeling in stylised physiological, pathological and post-surgical geometries. The results indicate that physiological sinus geometries cannot supply all the NO found in the nasal cavity. Pathological and post-surgical geometries have higher NO transport and lower steady-state NO concentrations than physiological geometries, but no difference was found between the two surgical techniques considered (inferior and middle meatal antrostomy). All the steady state concentrations are also above the level required for bacteriostatic effects.

本文言語English
ホスト出版物のタイトル6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech
ページ1145-1148
ページ数4
DOI
出版ステータスPublished - 2010 10 22
イベント6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech - Singapore, Singapore
継続期間: 2010 8 12010 8 6

出版物シリーズ

名前IFMBE Proceedings
31 IFMBE
ISSN(印刷版)1680-0737

Other

Other6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech
国/地域Singapore
CitySingapore
Period10/8/110/8/6

ASJC Scopus subject areas

  • 生体医工学
  • バイオエンジニアリング

フィンガープリント

「Numerical modeling of microvascular hemodynamics in plasmodium falciparum malaria」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル