Nucleotide Sequence of the Putative Human Tyrosinase Pseudogene

Atsushi Takeda, Shigeki Shibahara, Jun Matsunaga, Yasushi Tomita, Hachiro Tagami

研究成果: Article査読

11 被引用数 (Scopus)

抄録

We have cloned and sequenced the putative human tyrosinase pseudogene, which shares more than 98% nucleotide homology with exon 4 and exon 5 of the human tyrosinase gene including their flanking introns. Because of such a high homology, both the tyrosinase gene and its pseudogene could be amplified from genomic DNA by polymerase chain reaction. The nucleotide sequences presented thus enable us to discriminate the tyrosinase gene from its related sequences and are invaluable for a gene diagnosis of oculocutaneous albinism.

本文言語English
ページ(範囲)295-297
ページ数3
ジャーナルTohoku Journal of Experimental Medicine
163
4
DOI
出版ステータスPublished - 1991

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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