Nuclear actin activates human transcription factor genes including the OCT4 Gene

Shota Yamazaki, Koji Yamamoto, Makio Tokunaga, Kumiko Sakata-Sogawa, Masahiko Harata

研究成果: Article

6 引用 (Scopus)

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RNA microarray analyses revealed that nuclear actin activated many human transcription factor genes including OCT4, which is required for gene reprogramming. Oct4 is known to be activated by nuclear actin in Xenopus oocytes. Our findings imply that this process of OCT4 activation is conserved in vertebrates and among cell types and could be used for gene reprogramming of human cells.

元の言語English
ページ(範囲)242-246
ページ数5
ジャーナルBioscience, Biotechnology and Biochemistry
79
発行部数2
DOI
出版物ステータスPublished - 2015 1 1

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biotechnology
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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