Nonapoptotic functions of caspases: caspases as regulatory molecules for immunity and cell-fate determination

Erina Kuranaga, Masayuki Miura

研究成果: Review article査読

159 被引用数 (Scopus)

抄録

Caspases are a family of cysteine proteases that are highly conserved in multicellular organisms and function as central regulators of apoptosis. Recent investigations in Caenorhabditis elegans, Drosophila and mice suggest that caspases also function as regulatory molecules for immunity and cell-fate determination. Here, we review genetic studies of nonapoptotic functions of caspases and discuss the regulatory mechanisms of caspases for executing nonapoptotic functions.

本文言語English
ページ(範囲)135-144
ページ数10
ジャーナルTrends in Cell Biology
17
3
DOI
出版ステータスPublished - 2007 3
外部発表はい

ASJC Scopus subject areas

  • 細胞生物学

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