NK cells in innate immunity

Jessica A. Hamerman, Kouetsu Ogasawara, Lewis L. Lanier

研究成果: Review article査読

227 被引用数 (Scopus)

抄録

NK cells have an important role in innate immune responses, particularly in anti-viral immunity. Recent studies have revealed a molecular basis for NK cell recognition of virus-infected cells, implicating the activating KIR and Ly49 receptors and NKG2D in this process. Additionally, mutual cooperation between NK cells and dendritic cells suggests that these innate cells can shape the nature of an adaptive immune response. These findings, as well as advances in understanding NK cell development and homeostasis, indicate that NK cell biology is more sophisticated than previously appreciated.

本文言語English
ページ(範囲)29-35
ページ数7
ジャーナルCurrent Opinion in Immunology
17
1
DOI
出版ステータスPublished - 2005 2
外部発表はい

ASJC Scopus subject areas

  • 免疫アレルギー学
  • 免疫学

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