New insight into the mode of action of vancomycin dimers in bacterial cell wall synthesis

Osamu Yoshida; Jun Nakamura; Hidenori Yamashiro; Kenji Miura; Sayaka Hayashi; Kosei Umetsu; Shu Xu; Hideki Maki; Hirokazu Arimoto

doi:10.1039/c0md00230e

New insight into the mode of action of vancomycin dimers in bacterial cell wall synthesis

Osamu Yoshida, Jun Nakamura, Hidenori Yamashiro, Kenji Miura, Sayaka Hayashi, Kosei Umetsu, Shu Xu, Hideki Maki, Hirokazu Arimoto

研究成果: Article › 査読

15 被引用数 (Scopus)

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The emergence of vancomycin-resistant bacteria has created an urgent need for new active analogues of vancomycin. We previously reported vancomycin dimers with in vivo antibacterial activity. Here, we provide the first experimental insights into their inhibitory actions in bacterial cell wall synthesis.

本文言語	English
ページ（範囲）	278-282
ページ数	5
ジャーナル	MedChemComm
巻	2
号	4
DOI	https://doi.org/10.1039/c0md00230e
出版ステータス	Published - 2011 4月

ASJC Scopus subject areas

生化学
分子医療
薬理学
薬科学
創薬
有機化学

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10.1039/c0md00230e

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New insight into the mode of action of vancomycin dimers in bacterial cell wall synthesis

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