New anti-malarial phenylpropanoid conjugated iridoids from Morinda morindoides

Satoru Tamura, Bruno Kilunga Kubata, Syamsurizal, Sawako Itagaki, Toshihiro Horii, Muzele Kalulu Taba, Nobutoshi Murakami

研究成果: Article査読

19 被引用数 (Scopus)

抄録

A new phenylpropanoid conjugated iridoid together with four known congeners was isolated from Morinda morindoides, used for the therapy of malaria traditionally in some African countries, as anti-malarial principles through bioassay-guided separation. Furthermore, their absolute stereostructures were unambiguously established by a combination of modified Mosher's method and chemical correlation.

本文言語English
ページ(範囲)1520-1523
ページ数4
ジャーナルBioorganic and Medicinal Chemistry Letters
20
5
DOI
出版ステータスPublished - 2010 3 1

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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