New anti-malarial phenylpropanoid conjugated iridoids from Morinda morindoides

Satoru Tamura; Bruno Kilunga Kubata; Syamsurizal; Sawako Itagaki; Toshihiro Horii; Muzele Kalulu Taba; Nobutoshi Murakami

doi:10.1016/j.bmcl.2010.01.095

New anti-malarial phenylpropanoid conjugated iridoids from Morinda morindoides

Satoru Tamura, Bruno Kilunga Kubata, Syamsurizal, Sawako Itagaki, Toshihiro Horii, Muzele Kalulu Taba, Nobutoshi Murakami

理学研究科・化学専攻

研究成果: Article › 査読

19 被引用数 (Scopus)

抄録

A new phenylpropanoid conjugated iridoid together with four known congeners was isolated from Morinda morindoides, used for the therapy of malaria traditionally in some African countries, as anti-malarial principles through bioassay-guided separation. Furthermore, their absolute stereostructures were unambiguously established by a combination of modified Mosher's method and chemical correlation.

本文言語	English
ページ（範囲）	1520-1523
ページ数	4
ジャーナル	Bioorganic and Medicinal Chemistry Letters
巻	20
号	5
DOI	https://doi.org/10.1016/j.bmcl.2010.01.095
出版ステータス	Published - 2010 3 1

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

文献へのアクセス

10.1016/j.bmcl.2010.01.095

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引用スタイル

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AU - Horii, Toshihiro

AU - Taba, Muzele Kalulu

AU - Murakami, Nobutoshi

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KW - Anti-malarial

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