Neuropsychosocial features of very mild Alzheimer's disease (CDR 0.5) and progression to dementia in a community: The tajiri project

Kenichi Meguro, Masumi Shimada, Satoshi Yamaguchi, Iwao Sano, Hiroki Inagaki, Masaaki Matsushita, Yasuyoshi Sekita, Etsuro Mori

研究成果: Article査読

16 被引用数 (Scopus)

抄録

The borderline condition between normal aging and dementia should be detected to predict further deterioration. The authors cross-sectionally analyzed neuropsychological data, memory complaints, and social activities for community-dwelling older adults. The rate of decline from Clinical Dementia Rating (CDR) 0.5 to dementia during a 3-year interval was also analyzed. Short-term memory rather than long-term memory was found to be sensitive in distinguishing those with CDR O from those with CDR 0.5. Relatives' observations of memory decline rather than subjective memory complaints were significantly different. Participants with CDR 0.5 reported fewer problems with social activities than did their relatives. Ten of the 29 CDR 0.5 participants (34.5%) showed cognitive decline, the decliners showing lower scores on short-term memory and orientation at the baseline condition. The neuropsychological data showed CDR 0.5 to be similar to very mild Alzheimer's disease. It would be better if subjective complaints were excluded from the criteria of the borderline condition.

本文言語English
ページ(範囲)183-189
ページ数7
ジャーナルJournal of Geriatric Psychiatry and Neurology
17
4
DOI
出版ステータスPublished - 2004 12

ASJC Scopus subject areas

  • Clinical Neurology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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