Nectrianolins A, B, and C, new metabolites produced by endophytic fungus Nectria pseudotrichia 120-1NP

Nanang Rudianto Ariefta, Priska Kristiana, Handojo Hadi Nurjanto, Hiroyuki Momma, Eunsang Kwon, Tatsuya Ashitani, Keitaro Tawaraya, Tetsuya Murayama, Takuya Koseki, Hiroshi Furuno, Narandulam Usukhbayar, Ken ichi Kimura, Yoshihito Shiono

研究成果: Article査読

7 被引用数 (Scopus)

抄録

Two sesquiterpene-epoxycyclohexenone conjugates, nectrianolins A (1) and B (2), together with a sesquiterpene, nectrianolin C (3), were isolated from the brown rice culture of Nectria pseudotrichia 120-1NP, an endophytic fungus isolated from Gliricidia sepium. Their structures were determined on the basis of 1D-/2D-NMR spectroscopy and HRESIMS data analyses in combination with chemical means. Nectrianolins A–C (1–3) exhibited cytotoxic activity against both HL60 and HeLa cells.

本文言語English
ページ(範囲)4082-4086
ページ数5
ジャーナルTetrahedron Letters
58
43
DOI
出版ステータスPublished - 2017

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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