Murine chromosomal location of four class iii pou transcription factors

Karen B. Avraham, Brian C. Cho, Debra Gilbert, Hideta Fujii, Koji Okamoto, Takuya Shimazaki, Toshiro Ito, Hiroki Shoji, Yoshio Wakamatsu, Hisato Kondoh, Naoki Takahashi, Masami Muramatsu, Hiroshi Hamada, Neal G. Copeland, Nancy A. Jenkins

研究成果: Article

16 引用 (Scopus)

抜粋

A family of mouse genes encoding class III POU transcription factors consists of four members: Oct-6, Brn-2, Brn-1, and Brn-4. In accordance with mouse nomenclature, these loci have been designated Otf-6, Otf-7, Otf-8, and Otf-9, respectively. While the four genes share a highly conserved class III POU domain, the remaining regions are considerably diverged from each other. The POU domains of these transcription factors recognize the octamer-motif sequence and possess a similar DNA-binding specificity. Chromosomal mapping has demonstrated that the four genes are unlinked: Otf-6 is located on the distal region of chromosome 4, Otf-7 on the proximal region of chromosome 4, Otf-8 on chromosome 1, and Otf-9 on the X chromosome.

元の言語English
ページ(範囲)131-133
ページ数3
ジャーナルGenomics
18
発行部数1
DOI
出版物ステータスPublished - 1993 10
外部発表Yes

ASJC Scopus subject areas

  • Genetics

フィンガープリント Murine chromosomal location of four class iii pou transcription factors' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Avraham, K. B., Cho, B. C., Gilbert, D., Fujii, H., Okamoto, K., Shimazaki, T., Ito, T., Shoji, H., Wakamatsu, Y., Kondoh, H., Takahashi, N., Muramatsu, M., Hamada, H., Copeland, N. G., & Jenkins, N. A. (1993). Murine chromosomal location of four class iii pou transcription factors. Genomics, 18(1), 131-133. https://doi.org/10.1006/geno.1993.1436