MRI signal intensity based B-spline nonrigid registration for pre- and intraoperative imaging during prostate brachytherapy

Sota Oguro, Junichi Tokuda, Haytham Elhawary, Steven Haker, Ron Kikinis, Clare M.C. Tempany, Nobuhiko Hata

研究成果: Article査読

38 被引用数 (Scopus)

抄録

Purpose: To apply an intensity-based nonrigid registration algorithm to MRI-guided prostate brachytherapy clinical data and to assess its accuracy. Materials and Methods: A nonrigid registration of preoperative MRI to intraoperative MRI images was carried out in 16 cases using a Basis-Spline algorithm in a retrospective manner. The registration was assessed qualitatively by experts' visual inspection and quantitatively by measuring the Dice similarity coefficient (DSC) for total gland (TG), central gland (CG), and peripheral zone (PZ), the mutual information (MI) metric, and the fiducial registration error (FRE) between corresponding anatomical landmarks for both the nonrigid and a rigid registration method. Results: All 16 cases were successfully registered in less than 5 min. After the nonrigid registration, DSC values for TG, CG, PZ were 0.91, 0.89, 0.79, respectively, the MI metric was -0.19 ± 0.07 and FRE presented a value of 2.3 ± 1.8 mm. All the metrics were significantly better than in the case of rigid registration, as determined by one-sided t-tests. Conclusion: The intensity-based nonrigid registration method using clinical data was demonstrated to be feasible and showed statistically improved metrics when compare to only rigid registration. The method is a valuable tool to integrate pre- and intraoperative images for brachytherapy.

本文言語English
ページ(範囲)1052-1058
ページ数7
ジャーナルJournal of Magnetic Resonance Imaging
30
5
DOI
出版ステータスPublished - 2009 11
外部発表はい

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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