TY - JOUR
T1 - Mouse and human cell activation by N-dodecanoyl-DL-homoserine lactone, a Chromobacterium violaceum autoinducer
AU - Gomi, Kazunori
AU - Kikuchi, Toshiaki
AU - Tokue, Yutaka
AU - Fujimura, Shigeru
AU - Uehara, Akiko
AU - Takada, Haruhiko
AU - Watanabe, Akira
AU - Nukiwa, Toshihiro
PY - 2006/12
Y1 - 2006/12
N2 - Chromobacterium violaceum produces autoinducers, including homoserine lactones (HSLs), for genetic regulation. Among the seven HSLs derived from C. violaceum we evaluated, only C12-HSL stimulated the production of inflammatory cytokines in mammalian monocytic cell lines through the activation of the NF-κB signaling pathway besides their quorum-sensing role, like 3-oxo-C12-HSL from Pseudomonas aeruginosa.
AB - Chromobacterium violaceum produces autoinducers, including homoserine lactones (HSLs), for genetic regulation. Among the seven HSLs derived from C. violaceum we evaluated, only C12-HSL stimulated the production of inflammatory cytokines in mammalian monocytic cell lines through the activation of the NF-κB signaling pathway besides their quorum-sensing role, like 3-oxo-C12-HSL from Pseudomonas aeruginosa.
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UR - http://www.scopus.com/inward/citedby.url?scp=33845485492&partnerID=8YFLogxK
U2 - 10.1128/IAI.00038-06
DO - 10.1128/IAI.00038-06
M3 - Article
C2 - 16982829
AN - SCOPUS:33845485492
VL - 74
SP - 7029
EP - 7031
JO - Infection and Immunity
JF - Infection and Immunity
SN - 0019-9567
IS - 12
ER -
