Molecular mechanisms for defining tectum territory in chick embryogenesis

Yuji Watanabe, Tatsuya Katahira, Tatsuya Sato, Harukazu Nakamura

研究成果: Review article査読

1 被引用数 (Scopus)

抄録

Optic rectum derives from the midbrain alar plate in early chick development. To know the molecular mechanism defining rectum territory along the anteroposterior (AP) end dorsoventral (DV) axis in neural development, we have carried out the gain-of-function experiments using a newly developed gene transfer system, in ovo electroporation. Misexpression of Otx2/Gbx2 and Shh changed the expression of rectum-related genes, resulting in the fate change of the tectum structure along the AP axis end the DV axis, respectively. We conclude that these genes are involved in the establishment of rectum territory in embryogenesis.

本文言語English
ページ(範囲)1-4
ページ数4
ジャーナルACTA HISTOCHEMICA ET CYTOCHEMICA
33
1
DOI
出版ステータスPublished - 2000

ASJC Scopus subject areas

  • 病理学および法医学
  • 生化学
  • 生理学
  • 組織学
  • 細胞生物学

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