Molecular electrochemical switching element based on diffusive molecular competition for multipoint electrochemical detection of respiration activity of cell aggregates

Kosuke Ino, Yuta Yamada, Yusuke Kanno, Shunsuke Imai, Hitoshi Shiku, Tomokazu Matsue

研究成果: Article査読

10 被引用数 (Scopus)

抄録

Electrochemical techniques have been widely utilized for evaluation of oxygen consumption of cells. For high throughput cell analysis and imaging, several electrode-array devices have been developed. However, it is difficult to incorporate many sensors into a small area using a simple arrangement. In the present study, we developed a novel molecular electrochemical switching element for the incorporation of many sensors for detection of oxygen consumption of cells. The switching element is based on the competition of molecular consumption at an electrode pair. The switching elements are incorporated into an electrochemical imaging device, so that n2 electrochemical sensors are prepared with only 2n connector pads. The device was then applied to evaluate the respiratory activity of cell aggregates. The detection system is a useful tool for the electrochemical imaging of cell respiratory activity without any damage to samples.

本文言語English
ページ(範囲)201-208
ページ数8
ジャーナルSensors and Actuators, B: Chemical
234
DOI
出版ステータスPublished - 2016 10月 29

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 器械工学
  • 凝縮系物理学
  • 表面、皮膜および薄膜
  • 金属および合金
  • 電子工学および電気工学
  • 材料化学

フィンガープリント

「Molecular electrochemical switching element based on diffusive molecular competition for multipoint electrochemical detection of respiration activity of cell aggregates」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル