Modeling Approach for An Aortic Dissection with Endovascular Stenting

Yasuyuki Shiraishi, Tomoyuki Yambe, Andrew J. Narracott, Akihiro Yamada, Ryosuke Morita, Yi Qian, Kazuhiko Hanzawa

研究成果: Conference contribution

抄録

Repair of dissected aorta requires remodeling the structure of the media. Modeling approaches specific to endovascular stenting for aortic dissection have been reported. We created a goat model of descending thoracic aortic dissection and reproduced its morphological characteristics in a mock circulatory system. The purpose of this study was to examine a newly developed aortic stent which was capable of installing to the aortic dissected lesion for biomedical hemodynamics point of view. In this study, we examined the changes in hemodynamics of dissected lesions and the amelioration by endovascular stent intervention. Firstly, we performed animal experiments with the dissected aorta and examined the effects of stenting on volumetric changes in the false lumen. Secondly, we made several types of 3-D stereolithographic dissected aortic models with silicone rubber membrane between the false and the true lumens. Then, the hemodynamic characteristics in each model were evaluated in the pulsatile flow conditions in a mock circulatory system. These modelling approaches enabled the quantitative examination of post-therapeutic effects of stenting followed by elucidating of hemodynamic changes in the vicinity of stents, which may follow the management of clinical amelioration of interventional treatment with aortic stenting.Clinical Relevance - This study represents a modelling approach of the dissected aorta for endovascular intervention using stenting followed by the examination of false lumen volumetric changes resulting in the deterioration of pressure increase in diseased lesions.

本文言語English
ホスト出版物のタイトル42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society
ホスト出版物のサブタイトルEnabling Innovative Technologies for Global Healthcare, EMBC 2020
出版社Institute of Electrical and Electronics Engineers Inc.
ページ5008-5011
ページ数4
ISBN(電子版)9781728119908
DOI
出版ステータスPublished - 2020 7
イベント42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020 - Montreal, Canada
継続期間: 2020 7 202020 7 24

出版物シリーズ

名前Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
2020-July
ISSN(印刷版)1557-170X

Conference

Conference42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020
国/地域Canada
CityMontreal
Period20/7/2020/7/24

ASJC Scopus subject areas

  • 信号処理
  • 生体医工学
  • コンピュータ ビジョンおよびパターン認識
  • 健康情報学

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