Microtubule shuttles on kinesin-coated glass micro-wire tracks

Kyongwan Kim, Andrew L. Liao, Aurélien Sikora, Daniel Oliveira, Hikaru Nakazawa, Mitsuo Umetsu, Izumi Kumagai, Tadafumi Adschiri, Wonmuk Hwang, Winfried Teizer

研究成果: Article査読

6 被引用数 (Scopus)

抄録

Gliding of microtubule filaments on surfaces coated with the motor protein kinesin has potential applications for nano-scale devices. The ability to guide the gliding direction in three dimensions allows the fabrication of tracks of arbitrary geometry in space. Here, we achieve this by using kinesin-coated glass wires of micrometer diameter range. Unlike previous methods in which the guiding tracks are fixed on flat two-dimensional surfaces, the flexibility of glass wires in shape and size facilitates building in-vitro devices that have deformable tracks.

本文言語English
ページ(範囲)501-508
ページ数8
ジャーナルBiomedical microdevices
16
4
DOI
出版ステータスPublished - 2014 8

ASJC Scopus subject areas

  • 生体医工学
  • 分子生物学

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